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KMID : 1101420140460010017
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Korean Journal of Clinical Laboratory Science
2014 Volume.46 No. 1 p.17 ~ p.21
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Epidemiologic Study on Hepatitis A Virus Seroprevalence in Busan
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Cho Kyung-Soon
Park So-Hyun
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Abstract
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The prevalence of hepatitis A virus (HAV) in a certain community reflects that community's living standard and hygienic condition. The seroprevalence rate of IgG anti-HAV has been changing with regions and times. In this study, we aimed to study the difference of seroprevalence of IgG anti-HAV according to sex, age and type of drinking water, and to know the vaccination rate and seroconversion rate for vaccinated subjects in Busan. A total of 644 samples were analyzed. The overall seroprevalence rate of IgG anti-HAV was 35.4% (228/644). There was no significant difference in sex (male 39.8%, female 32.7) (p＞0.05). According to age, seroprevalence rate of anti-HAV were 55.0% in subjects aged 5∼9 years old, 47.8% in 10∼14 years old, decreced to 10.6% in 15∼19 years old, 1.0% in 20∼24 years old, 0.0% in 25∼29 years old and increced with advacing ages ; 14.7% in 30∼34 years old, 39.4% in 35∼39 years old, 67.3% in 40∼44 years old, 94.1% in 45∼49 years old, 100.0% over 50 years (p＜0.001). The seroprevalence of IgG anti-HAV was no statistical difference according to the types of drinking water (p＞0.05). The vaccinated subject was 42 case only in below 25 years old. The seroconversion rate after vaccination was 88.1%.
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KEYWORD
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Drinking water, Hepatitis A virus (HAV), Seroprevalence, Seroconversion rate, Vaccination rate
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